Ferulic Acid Suppresses Amyloid β Production in the Human Lens Epithelial Cell Stimulated with Hydrogen Peroxide

Figure 3

The effect of ferulic acid on Aβ_1–40 (a), Aβ_1–42 (b), Aβ_1–43 (c), and cell viability (d) in 10 μM H₂O₂-stimulated HLE cells. The 10 μM H₂O₂ and 0–30 μM ferulic acid were added simultaneously to the medium, and the HLE cells were incubated for 24 h. Open columns = H₂O₂-stimulated HLE cells. Closed columns = H₂O₂-stimulated HLE cells with ferulic acid treatment. The data are presented as the means ± SE of 5–8 experiments. , versus H₂O₂-stimulated HLE cells in the absence of ferulic acid (open columns) for each category.

(a) Aβ_1–40 levels

(b) Aβ_1–42 levels

(c) Aβ_1–43 levels

(d) Cell viability