Research Article

Pharmacokinetics and Pharmacodynamics Evaluation of Tramadol in Thermoreversible Gels

Figure 1

Time-course (min) after the injection of TR formulations in rabbits. Values are expressed as mean ± SD. F4 < F1 and F2 and F3 after 30 to 60 min (); F4 < F2 and F3 after 90 min (). F2 > F1 and F4 after 120 min and after 180 min F2 > F1 and F3 and F4 ().