miR-373-3p Targets DKK1 to Promote EMT-Induced Metastasis via the Wnt/-Catenin Pathway in Tongue Squamous Cell Carcinoma

Figure 1

miR-373-3p is upregulated in TSCC tissues and correlates with metastatic capacity. (a) Expression of miR-373-3p in an independent validation cohort of 63 pairs of matching normal and TSCC tissues. (b) Mean values of miR-373-3p relative levels from TSCC tissues including a group of 46 TSCC patients with positive lymph node metastases compared to the control group of 15 TSCC patients with negative lymph node metastases. (c) Expression levels of miR-373-3p in normal tongue squamous cells (NTSCs) and five TSCC cell lines (SCC-9, SCC-15, SCC-25, UM1, and UM2). All assays were performed in duplicate. , , and .

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