Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD

Figure 10

Correlation analysis of genes, proteins, and metabolites regulated in COPD rat and BJF-treated rat lung tissues. Metabolites-gene network analysis of COPD model (a) and BJF-treated group (b). Metabolites-protein network analysis of COPD model (c) and BJF-treated group (d). Networks of the metabolites, genes, and proteins were visualized by Metscape (hexagon node: compounds, round node: metabolic enzymes, and edge: reactions. Red: inputted genes and proteins; blue: inputted compounds).

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