Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD

Figure 5

Effect of BJF on MMP-2, MMP-9, and TIMP-1 expression in the COPD rat lung tissue. Immunohistochemical analysis for MMP-2, MMP-9, and TIMP-1 expression in the lung tissues was performed on week 32 (magnification, ×100) (a). Quantitative analysis expression level of MMP-2, MMP-9, and TIMP-1 was quantified based on the immunohistochemical testing (b). Values represent means ± SEM and . and versus model.

(a)

(b)