Research Article

Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD

Table 2

Related pathways of transcriptomics detected in BJF-treated rats lung tissue.

TermCount% value

Ribosome290.174751
Aminoacyl-tRNA biosynthesis110.066285
Endocytosis300.180777
Prostate cancer170.102440.001294
Renal cell carcinoma140.0843630.002109
Ubiquitin mediated proteolysis200.1205180.00352
Neurotrophin signaling pathway200.1205180.00352
Adherens junction140.0843630.004004
Tight junction200.1205180.005003
Citrate cycle (TCA cycle)80.0482070.006777
MAPK signaling pathway320.1928290.013297
Proteasome100.0602590.013316
Nucleotide excision repair90.0542330.015824
N-Glycan biosynthesis90.0542330.018075
Spliceosome170.102440.023539
Oxidative phosphorylation180.1084660.03465
Antigen processing and presentation130.0783370.037581
Propanoate metabolism70.0421810.038533
Endometrial cancer90.0542330.040556
Amino sugar and nucleotide sugar metabolism80.0482070.045144