Research Article

Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD

Table 3

Related pathways of proteins identified in COPD rats lung tissue.

TermCount% value

ECM-receptor interaction80.36660.0002
Focal adhesion110.50410.0006
Leukocyte transendothelial migration70.32080.0069
Glycolysis/gluconeogenesis60.27500.0079
Propanoate metabolism40.18330.0125
Pyruvate metabolism40.18330.0196
Tryptophan metabolism40.18330.0254
Valine, leucine, and isoleucine degradation40.18330.0303
Small cell lung cancer50.22910.0343
Regulation of actin cytoskeleton80.36660.0348
Tight junction60.27500.0433
Nitrogen metabolism30.13750.0450
Pentose phosphate pathway30.13750.0487