Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD

Table 5

Related pathways of metabolites identified in COPD rat lung tissue.

Term	Total	Expected	Hits	Raw
Biosynthesis of unsaturated fatty acids	42	0.6591	6
Arachidonic acid metabolism	36	0.5649	4	0.001929
Linoleic acid metabolism	5	0.0785	2	0.002286
Sphingolipid metabolism	21	0.3295	3	0.003718
Glycerophospholipid metabolism	30	0.4708	3	0.010353
Cyanoamino acid metabolism	6	0.0942	1	0.09069
alpha-Linolenic acid metabolism	9	0.1412	1	0.13304
Methane metabolism	9	0.1412	1	0.13304
Fatty acid biosynthesis	43	0.6748	2	0.1443
Steroid hormone biosynthesis	70	1.0984	2	0.3014
Cysteine and methionine metabolism	28	0.4394	1	0.36059
Glycine, serine, and threonine metabolism	32	0.5021	1	0.40061
Steroid biosynthesis	35	0.5492	1	0.42905
Primary bile acid biosynthesis	46	0.7218	1	0.52269
Aminoacyl-tRNA biosynthesis	67	1.0514	1	0.66232