Integrating Transcriptomics, Proteomics, and Metabolomics Profiling with System Pharmacology for the Delineation of Long-Term Therapeutic Mechanisms of Bufei Jianpi Formula in Treating COPD

Table 6

Related pathways of metabolites identified in BJF-treated rat lung tissue.

Term	Total	Expected	Hits	Raw
Arachidonic acid metabolism	36	0.8217	7
Biosynthesis of unsaturated fatty acids	42	0.9586	5	0.002093
Linoleic acid metabolism	5	0.1141	2	0.004837
Glycerophospholipid metabolism	30	0.6847	3	0.028867
Glutathione metabolism	26	0.5934	2	0.11684
alpha-Linolenic acid metabolism	9	0.2054	1	0.18812
Fatty acid biosynthesis	43	0.9815	2	0.25705
Selenoamino acid metabolism	15	0.3424	1	0.29397
Histidine metabolism	15	0.3424	1	0.29397
Butanoate metabolism	20	0.4565	1	0.37185
Sphingolipid metabolism	21	0.4793	1	0.38639
Alanine, aspartate, and glutamate metabolism	24	0.5478	1	0.4281
Pyrimidine metabolism	41	0.9358	1	0.61733
Arginine and proline metabolism	44	1.0043	1	0.64371
Aminoacyl-tRNA biosynthesis	67	1.5292	1	0.79506
Purine metabolism	68	1.5521	1	0.79997