Tyrosine Phosphorylation of NR2B Contributes to Chronic Migraines via Increased Expression of CGRP in Rats

Figure 3

Inhibition of NR2B tyrosine phosphorylation led to protective function on allodynia at 24 hours and 72 hours after genistein treatment. Paw withdrawal (a, c) and face (b, d) threshold showed that high dosage of genistein led to both short- and long-term protective function on allodynia. versus sham; versus CM-vehicle; for each group.

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