| | Blood loss (mL) | ICS | Controls | P (ICS versus controls) |
| PT-pre (s) | 1200–1599 | 13.85 (12.4, 21.7) | 13.9 (12, 17.5) | 0.655 | 1600–1999 | 14.05 (12.7, 15.6) | 14 (12.7, 15) | 0.851 | 2000–2399 | 14.1 (12.3, 21.9) | 13.9 (12.2, 16.9) | 0.328 | 2400–2799 | 13.5 (11.1, 18.4) | 13.7 (12.3, 16.6) | 0.890 | 2800–3199 | 13.0 (12.4, 14.7) | 13.7 (12.9, 15.2) | 0.189 | ≥3200 | 14.2 (12.7, 14.6) | 15.65 (13, 28.6) | 0.200 |
| PT-post (s) | 1200–1599 | 14.7 (11.7, 20.0) | 13.9 (10.3, 20) | 0.033 | 1600–1999 | 13.8 (12.5, 19.0) | 15.3 (10.2, 16.3) | 0.767 | 2000–2399 | 14.3 (11.2, 19.8) | 13.85 (10.7, 17.2) | 0.097 | 2400–2799 | 13.6 (12.3, 19.9) | 13.8 (10.8, 16.3) | 0.828 | 2800–3199 | 14.0 (11.1, 15.3) | 14.05 (11.3, 16.3) | 0.955 | ≥3200 | 14.2 (12.8, 15.2) | 14.35 (13.2, 21.6) | 0.686 |
| PT-INR-pre | 1200–1599 | 1.07 (0.96, 1.85 | 1.07 (0.87, 1.43) | 0.661 | 1600–1999 | 1.12 (0.93, 1.25) | 1.09 (0.95, 1.17) | 0.403 | 2000–2399 | 1.09 (0.91, 1.86) | 1.07 (0.89, 1.35) | 0.492 | 2400–2799 | 1.06 (0.93, 1.54) | 1.04 (0.9, 1.35) | 1.000 | 2800–3199 | 0.99 (0.96, 1.15) | 1.08 (0.98, 1.15) | 0.121 | ≥3200 | 1.11 (0.95, 1.14) | 1.23 (0.97, 1.58) | 0.200 |
| PT-INR-post | 1200–1599 | 1.14 (0.95, 1.68 | 1.07 (0.88, 1.56) | 0.009 | 1600–1999 | 1.07 (0.91, 1.57) | 1.19 (0.92, 1.29) | 0.609 | 2000–2399 | 1.12 (0.91, 1.65) | 1.07 (0.9, 1.38) | 0.434 | 2400–2799 | 1.02 (0.9, 1.67) | 1.04 (0.89, 1.29) | 1.000 | 2800–3199 | 1.07 (0.85, 1.23) | 1.06 (0.9, 1.29) | 0.955 | ≥3200 | 1.08 (0.94, 1.21) | 1.09 (0.98, 1.85) | 0.686 |
| APTT-pre (s) | 1200–1599 | 33.7 (23.6, 49.4 | 33.4 (23.2, 45.4) | 0.848 | 1600–1999 | 33.8 (29, 48.6) | 33.2 (26.6, 45 | 0.851 | 2000–2399 | 33.6 (26.3, 44.6) | 32.2 (22.4, 46.8) | 0.304 | 2400–2799 | 31.9 (23.6, 49.4) | 32.8 (26.8, 39.8) | 0.293 | 2800–3199 | 33.0 (22.3, 37.9) | 33.6 (31.6, 39.8) | 0.779 | ≥3200 | 33.0 (31.7, 40.5) | 30.7 (29, 53.4) | 0.486 |
| APTT-post (s) | 1200–1599 | 35.8 (28.1, 45.1 | 34.2 (23.8, 49.1) | 0.236 | 1600–1999 | 35.2 (31.2, 48.9) | 36.2 (24.3, 48.1 | 0.936 | 2000–2399 | 34.2 (28.8, 47.5) | 33.2 (27.3, 42.8) | 0.287 | 2400–2799 | 33.9 (27.4, 44.7) | 33.6 (26.8, 44.3) | 0.650 | 2800–3199 | 37.0 (20.4, 38.8) | 35.2 (30.2, 44.2) | 0.779 | ≥3200 | 33.8 (29.3, 44.2) | 35.5 (28.7, 50.2) | 1.000 |
| FIB-pre (g/L) | 1200–1599 | 2.49 (0.95, 4.28) | 2.31 (0.72, 6.10) | 0.497 | 1600–1999 | 2.24 (1.59, 3.95) | 2.69 (2.12, 4.17) | 0.107 | 2000–2399 | 2.51 (1.39, 4.83) | 2.67 (1.51, 3.93) | 0.801 | 2400–2799 | 2.36 (1.31, 3.79) | 2.64 (1.42, 3.88) | 0.051 | 2800–3199 | 2.46 (1.81, 3.47) | 2.67 (2.34, 4.14) | 0.397 | ≥3200 | 2.54 (2.21, 2.84) | 2.05 (0.73, 2.90) | 0.486 |
| FIB-post (g/L) | 1200–1599 | 2.37 (0.76, 3.81) | 2.33 (1.09, 4.42) | 0.918 | 1600–1999 | 2.20 (1.18, 3.33) | 2.31 (1.10, 3.45) | 0.979 | 2000–2399 | 2.58 (1.21, 3.69) | 2.5 (1.45, 3.78) | 0.753 | 2400–2799 | 2.29 (1.07, 4.2) | 2.42 (1.75, 3.56) | 0.489 | 2800–3199 | 2.58 (1.90, 3.54) | 2.31 (2.03, 3.02) | 0.779 | ≥3200 | 2.56 (1.62, 3.65) | 2.12 (1.65, 3.65) | 0.686 |
| TT-pre (s) | 1200–1599 | 16.6 (13.5, 21.8) | 16.0 (13.3, 21.9) | 0.128 | 1600–1999 | 15.9 (14.3, 17.7) | 15.5 (13.7, 18.8) | 0.501 | 2000–2399 | 16.2 (13.7, 21.8) | 15.1 (13.5, 17.1) | <0.001 | 2400–2799 | 16.4 (14.3, 20.3) | 15.4 (14.5, 19) | 0.089 | 2800–3199 | 17.2 (13, 18.7) | 15.1 (13.7, 17.1) | 0.054 | ≥3200 | 16.7 (14.7, 19) | 15.6 (14.7, 20.3) | 0.886 |
| TT-post (s) | 1200–1599 | 15.6 (12.7, 22.6) | 15.3 (13.1, 26) | 0.690 | 1600–1999 | 15.3 (13.5, 17.8) | 17.2 (13.7, 17.9) | 0.647 | 2000–2399 | 16.3 (13.2, 19.6) | 15.2 (11.5, 17.8) | 0.001 | 2400–2799 | 15.6 (13.1, 20.6) | 15.1 (12.4, 17.6) | 0.312 | 2800–3199 | 13.9 (11.7, 18.3) | 15.3 (14.6, 19.7) | 0.072 | ≥3200 | 15.9 (15.2, 17.8) | 16.5 (14.2, 18.9) | 1.000 |
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