MET18 Deficiency Increases the Sensitivity of Yeast to Oxidative Stress and Shortens Replicative Lifespan by Inhibiting Catalase Activity

Figure 2

Effects of MET18 deficiency on enzymatic defense system against oxidative stress. Total SOD activity (a), catalase activity (b), CTA1 and CTT1 mRNA levels (c), and intracellular H₂O₂ levels (d) under unstressed condition were determined and compared between WT and MET18/met18Δ cells. Results shown are representative of three independent experiments. , versus WT cells ().

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