Research Article
Interferon-Gamma Release Assay Performance of Cerebrospinal Fluid and Peripheral Blood in Tuberculous Meningitis in China
Table 1
Clinical characteristics in study population (
).
| | Characteristics | TBM group
() | Non-TBM group
() | value |
| | Age, median (IQR), yrs | 31 (23–45) | 27 (23–47) | 0.938 | | Gender (female/male) | 19/34 | 9/28 | 0.245 | | HIV infection | 0 | 2 | 0.087 | | Cause of diseases | | | | | Tuberculous meningitis | 53 | NA | NA | | Viral meningitis | NA | 22 | NA | | Purulent meningitis | NA | 4 | NA | | Cryptococcal meningitis | NA | 4 | NA | | Meningeal malignant tumor | NA | 2 | NA | | Subarachnoid hemorrhage | NA | 1 | NA | | Other causes | NA | 4 | NA | | Underlying diseases | | | | | Diabetes mellitus | 4 | 3 | 0.922 | | Viral hepatitis | 2 | 2 | 0.712 | | SLE | 1 | 0 | 0.414 | | Myeloma | 1 | 0 | 0.414 | | CSF profile | | | | | Total WBC count, median cell ×103/ml (IQR) | 54 (20–116) | 15 (6.5–72) | 0.006 | | Lymphocyte count, median cell ×103/ml (IQR) | 45 (19–80) | 12 (5.5–63) | 0.002 | | ADA, median U/L (IQR) | 4.1 (1.9–6.0) | 2.2 (1.75–3.0) | 0.005 | | CSF/serum glucose ratio, median ratio (IQR) | 0.45 (0.38–0.56) | 0.64 (0.50–0.70) | <0.001 | | Glucose, median mmol/L (IQR) | 2.20 (1.73–2.75) | 3.10 (2.80–3.65) | <0.001 | | Protein level, median g/L (IQR) | 0.75 (0.63–1.10) | 0.40 (0.30–0.90) | 0.001 | | Chloride concentration, median mmol/L (IQR) | 117.1 (112.6–121.0) | 120.1 (118.5–122.0) | 0.003 |
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Note. NA: not applicable; IQR: interquartile range.
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