Research Article

Ameliorative Effect of Cactus (Opuntia ficus indica) Extract on Lithium-Induced Nephrocardiotoxicity: A Biochemical and Histopathological Study

Table 4

Kidney and heart malondialdehyde levels, nonenzymatic antioxidant levels (TSH), and enzymatic antioxidant activities (glutathione peroxidase, catalase, and superoxide dismutase) in male rat controls or those treated with lithium (Li), cactus cladodes extract (CCE), and cactus cladodes extract + lithium (CCE + Li) during 60 days.

ParametersCLiCCECCE + Li

MDA (nmol/mg protein)
 Heart
 Kidney
SOD (U/mg of protein)
 Heart
 Kidney
CAT (μmol/min/mg of protein)
 Heart
 Kidney
GPx (μmol GSH oxidized/min/mg of protein)
 Heart
 Kidney
TSH (U/mg protein)
 Heart
 Kidney

Values were expressed as mean ± SEM of 6 rats in group; compared with control (C); , compared with lithium carbonate-treated group (Li).