Research Article

Effect of Pregnancy on Quantitative Medication Use and Relation to Exacerbations in Asthma

Table 1

Ranking of asthma medication according to the guideline-based stepwise approach.

Component TypeRankPrescription period

LTRAs
 MontelukastOral11
 PranlukastOral11
 ZafirlukastOral11
Xanthine
 AminophyllineOral11
 TheophyllineOral11
LABA
 BambuterolOral11
 FenoterolOral11
 FormoterolOral11
 ProcaterolOral11
 ProcaterolInhaler130
 TerbutalineOral11
ICS
 Low-dose ICS
  BudesonideInhaler130
  CiclesonideInhaler130
  Fluticasone propionateInhaler130
 Medium- to high-dose ICS
  BudesonideInhaler230
  Fluticasone propionateInhaler230
ICS/LABA
 Low-dose ICS/LABA
  Budesonide/formoterolInhaler230
  Inhaler2
  Beclomethasone dipropionate/formoterolInhaler230
  Fluticasone furoate/vilanterolInhaler230
  Fluticasone propionate/formoterolInhaler230
  Fluticasone propionate/salmeterolInhaler230
  Inhaler2
 Medium- to high-dose ICS/LABA
  Budesonide/formoterolInhaler330
  Fluticasone propionate/salmeterolInhaler330
  Inhaler3
  Fluticasone propionate/formoterolInhaler330
  Fluticasone furoate/vilanterolInhaler330
LAMA
 TiotropiumInhaler430
Systemic corticosteroids
 Betamethasone < 2.4 mg41
 Dexamethasone < 3 mg41
 Methylprednisolone < 16 mg41
 Prednisolone < 20 mg41

device contains 120 doses, twice the dose of the standard device. device contains 28 doses for use over 14 days; LTRA, leukotriene receptor antagonist; LABA, long-acting -agonists; ICS, inhaled corticosteroid; LAMA, long-acting muscarinic antagonists.