Research Article
Effect of Pregnancy on Quantitative Medication Use and Relation to Exacerbations in Asthma
Table 2
Comparison of oral asthma medications before, during, and after pregnancy.
| Medication | Group | Before pregnancy | During pregnancy | After pregnancy | | Days/month | | Mean ± sd | Mean ± sd | Mean ± sd | |
| LTRAs | Total | | | | <0.0001 | Group 1 | | | | 0.0003 | Group 2 | | | | <0.0001 | Group 3 | | | | <0.0001 | Group 4 | | | | <0.0001 |
| Xanthine | Total | | | | <0.0001 | Group 1 | | | | 0.3094 | Group 2 | | | | <0.0001 | Group 3 | | | | <0.0001 | Group 4 | | | | <0.0001 |
| LABA | Total | | | | <0.0001 | Group 1 | | | | <0.0001 | Group 2 | | | | <0.0001 | Group 3 | | | | <0.0001 | Group 4 | | | | <0.0001 |
| Low-dose systemic corticosteroids | Total | | | | <0.0001 | Group 1 | | | | <0.0001 | Group 2 | | | | <0.0001 | Group 3 | | | | <0.0001 | Group 4 | | | | <0.0001 |
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value according to the multivariate analysis of variance; LTRA, leukotriene receptor antagonist; LABA, long-acting -agonists; sd, standard deviation.
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