Research Article

Effect of Pregnancy on Quantitative Medication Use and Relation to Exacerbations in Asthma

Table 2

Comparison of oral asthma medications before, during, and after pregnancy.

MedicationGroupBefore pregnancyDuring pregnancyAfter pregnancy
Days/month
Mean ± sdMean ± sdMean ± sd

LTRAsTotal<0.0001
Group 10.0003
Group 2<0.0001
Group 3<0.0001
Group 4<0.0001

XanthineTotal<0.0001
Group 10.3094
Group 2<0.0001
Group 3<0.0001
Group 4<0.0001

LABATotal<0.0001
Group 1<0.0001
Group 2<0.0001
Group 3<0.0001
Group 4<0.0001

Low-dose systemic corticosteroidsTotal<0.0001
Group 1<0.0001
Group 2<0.0001
Group 3<0.0001
Group 4<0.0001

value according to the multivariate analysis of variance; LTRA, leukotriene receptor antagonist; LABA, long-acting -agonists; sd, standard deviation.