Hypoxia Induces Apoptosis through HIF-1α Signaling Pathway in Human Uterosacral Ligaments of Pelvic Organ Prolapse

Figure 1

The expression of HIF-1α and BNIP3 are upregulated in USL tissues of the POP group. (a) Representative immunohistochemical staining of HIF-1α and BNIP3 in the uterosacral ligaments in control and POP group (magnification, ×200; scale bar = 10 μm). (b) Quantification of the expression of HIF-1α and BNIP3 between the POP group and the control group at the mRNA level. . (c and d) HIF-1α and BNIP3 were detected by Western blot analysis at the protein level. . .

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