Circulating MicroRNA Profiles Differ between Hyperglycemia and Euglycemia in Coronary Heart Disease Patients

Table 3

Specific pathways enriched by targets of differentially expressed miRNAs in HCHD group. (a) Top 10 significant upregulated pathways. (b) Significant downregulated pathway.

(a)

KEGG pathway	FDR adjusted value	Genes	miRNAs
TNF signaling pathway	4.8E–04	30	12
Hippo signaling pathway	0.0013	52	14
Signaling pathways regulating pluripotency of stem cells	0.0017	49	12
Non-small cell lung cancer	0.003	26	12
Epstein-Barr virus infection	0.004	60	12
HTLV-I infection	0.010	74	14
Small cell lung cancer	0.011	33	13
PI3K-Akt signaling pathway	0.015	93	14
Glioma	0.022	27	13
TGF-beta signaling pathway	0.024	32	11

(b)

KEGG pathway	FDR adjusted value	Genes	miRNAs
Viral carcinogenesis	0.019	20	2