Pregnancy during Adolescence and Associated Risks: An 8-Year Hospital-Based Cohort Study (2007–2014) in Romania, the Country with the Highest Rate of Teenage Pregnancy in Europe

Table 2

Risk of pregnancy comorbidities among teenagers in comparison with young adults (20–24 years of age).

Comorbidity; ICD-10 RR [CI]	Age 12–17	Age 18-19	Age 12–19	Age 20–24
Age of the study group (mean ± SD)	16.35 ± 0.88	18.55 ± 0.497	17.81 ± 1.25	22.18 ± 1.42
Chronic/gestational hypertension; O10; O13 RR [CI]	54 (4.23%); 1.06 [0.80–1.41]	93 (3.55%); 0.89 [0.71–1.12]	147 (3.77%); 0.95 [0.79–1.15]	375 (3.95%)
Preeclampsia; O14.0-O14.1 RR [CI]	5 (0.39%); 1.68 [0.64–4.45]	7 (0.54%); 1.15 [0.49–2.69]	12 (0.30%); 1.32 [0.65–2.68]	22 (0.23%)
Foetal anomalies; O35 RR [CI]	0	6 (0.22%); 0.77 [0.32–1.87]	6 (0.15%); 0.52 [0.21–1.27]	28 (0.29%)
Anaemia; O99.0 RR [CI]	873 (68.41%); 1.16 [1.12–1.21]	1722 (65.85%); 1.12 [1.08–1.16]	2595 (66.69%); 1.13 [1.10–1.17]	5557 (58.62%)
Diabetes (gestational, pregestational); O24.41-42; O24.0 RR [CI]	1 (0.07%); 0.22 [0.03–1.64]	3 (0.11%); 0.32 [0.10–1.07]	4 (0.10%); 0.30 [0.10–0.84]	33 (0.34%)
Obesity; O26.0 RR [CI]	59 (0.39%); 0.39 [0.16–0.96]	18 (0.68%); 0.69 [0.42–1.14]	23 (0.59%); 0.59 [0.37–0.93]	94 (0.99%)
Low urinary tract infection; O23.1; O86.21 RR [CI]	344 (26.95%); 1.18 [1.07–1.30]	637 (24.35%); 1.06 [0.99–1.15]	981 (25.21%); 1.10 [1.03–1.18]	2159 (22.77%)
High urinary tract infection; O23.0; O86.2.2 RR [CI]	1 (0.07%); 0.23 [0.03–1.75]	4 (0.15%); 0.46 [0.16–1.32]	5 (0.12%); 0.39 [0.15–1.02]	31 (0.32%)
Pediculosis; B85 RR [CI]	78 (6.11%); 3.76 [2.88–4.90]	75 (2.86%); 1.76 [1.34–2.31]	153 (3.93%); 2.42 [1.90–3.00]	154 (1.62%)
Anogenital condyloma; A63.0 RR [CI]	24 (1.88%); 2.40 [1.52–3.80]	21 (0.80%); 1.02 [0.63–1.66]	45 (1.15%); 1.50 [1.04–2.17]	74 (0.78%)
Lues/syphilis; O98.1 RR [CI]	7 (0.54%); 1.52 [0.67–3.44]	16 (0.61%); 1.70 [0.94–3.08]	23 (0.59%); 1.66 [0.98–2.83]	34 (0.35%)
Trichomonas; A59.0 RR [CI]; p	12 (0.94%); 1.81 [0.97–3.40]	23 (0.87%); 1.70 [1.03–2.78]	35 (0.89%); 1.74 [1.12–2.68]	49 (0.51%)
E. coli; B96.2 RR [CI]	192 (15.04%); 1.25 [1.09–1.45]	311 (11.89%); 0.99 [0.88–1.11]	503 (12.92%); 1.08 [0.98–1.10]	1133 (11.95%)
Streptococcus; B95.0; B95.1 RR [CI]	54 (4.23%); 0.89 [0.68–1.18]	107 (4.09%); 0.85 [0.69–1.04]	161 (4.13%); 0.87 [0.73–1.04]	467 (4.92%)
Staphylococcus; B95.6-8 RR [CI]	89 (6.97%); 1.04 [0.84–1.29]	139 (5.31%); 0.78 [0.65–0.95]	228 (5.85%); 0.87 [0.75–1.01]	671 (7.07%)
Klebsiella; B96.1 RR [CI]	23 (1.80%); 1.68 [1.07–2.64]	18 (0.68%); 0.64 [0.39–1.06]	41 (1.05%); 0.98 [0.68–1.41]	102 (1.07%)
Candida; B37.3 RR [CI]; P	18 (1.41%); 1.81 [1.08–3.03]	19 (0.72%); 0.93 [0.56–1.54]	37 (0.95%); 1.22 [0.82–1.81]	74 (0.78%)
Gardnerella vaginalis; B96.89 RR [CI]	0	2 (0.07%); 1.20 [0.24–5.90]	2 (0.05%); 0.81 [0.16–4.02]	6 (0.06%)
HIV infection; O98.7 RR [CI]	2 (0.15%); 0.74 [0.17–3.17]	4 (0.15%); 0.72 [0.24–2.11]	6 (0.15%); 0.73 [0.29–1.81]	20 (0.21%)
Hepatitis B and hepatitis C; B18.0-2 RR [CI]	3 (0.23%); 0.22 [0.07–0.69]	15 (0.57%); 0.53 [0.31–0.92]	18 (0.46%); 0.43 [0.26–0.71]	101 (1.06%)
Premature rupture of membranes; O42 RR [CI]	261 (20.45%); 0.75 [0.67–0.84]	702 (26.84%); 0.98 [0.91–1.05]	963 (24.74%); 0.90 [0.85–0.96]	2581 (27.22%)
Chorioamnionitis; O41.1 RR [CI]	16 (1.25%); 0.47 [0.28–0.78]	73 (2.79%); 1.06 [0.82–1.37]	89 (2.28%); 0.87 [0.68–1.10]	249 (2.62%)
Placenta praevia; O44.0-1 RR [CI]	9 (0.70%); 0.22 [0.11–0.43]	27 (1.03%); 0.32 [0.22–0.48]	36 (0.92%); 0.29 [0.20–0.41]	297 (3.13%)