Treatment with Sildenafil and Donepezil Improves Angiogenesis in Experimentally Induced Critical Limb Ischemia

Figure 3

Histochemical evaluation of capillary density in gastrocnemius muscle sections from Wistar rats, at the 4 experimental times (scale bar is 50 μm). Quantification of the number of CD31 positive cells/mm²: the graph illustrates the mean and standard deviation for each experimental variant. Statistical differences are marked: compared to the negative control group, compared to the ligation control group, and compared to the sildenafil treated group.