Matrix Metalloproteinase-9 Is a Predictive Factor for Systematic Hypertension and Heart Dysfunction in Patients with Obstructive Sleep Apnea Syndrome

Figure 1

Correlations between MMP-9 and sleep parameters in OSAS patients. (a) General view of polysomnographic parameters according to OSAS severity (Student’s t-test). The serum MMP-9 level was positively correlated with AHI (b) and ODI (c). Although no significant correlation was observed between MMP-9 and ESS (d), higher serum MMP-9 level (e) was associated with higher MAP according to Spearman correlation test. AHI: Apnea Hypopnea Index; ODI: Oxygen Desaturation Index; ESS: Epworth Sleepiness Scale; SpO₂: blood oxygen saturation; L-SpO₂: lowest SpO₂ during sleep; M-SpO₂: mean SpO₂ during sleep; MAP: mean arterial pressure. compared with mild group.

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