Increased Autophagy Levels Mediate Cisplatin Resistance in Cisplatin-Resistant Cells While Also Rendering Them Vulnerable to Autophagy Induction

Figure 7

Rapamycin inhibits ddp-resistant tumor growth in vivo. (a) Resected tumors from each group (n=6 in the rapamycin group, n=5 in the solvent group). (b) Tumor growth kinetics; treatment was stopped after 14 days. Error bars indicate the s.e.m. (c) Body weights of mice in the two groups throughout the treatment period. The error bars indicate s.d. P<0.05 and P<0.01.

(a)

(b)

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