Antimicrobial Activity of Cerium Oxide Nanoparticles on Opportunistic Microorganisms: A Systematic Review

Table 2

Recent studies of antimicrobial activity of CeNP against Staphylococcus aureus.

S. aureus strains	Concentration; (mg/mL)	Microbiological technique	Result
8325-4 CSGR	0.017	CFU count	No significant sensitivity		[7]
	0.17		1.53 ± 0.07 1 g CFU/mL
	1.72		No significant sensitivity
ATCC (number ni)	1.37	Time and kill	Inhibition ~40%		[15]
	2.58–3.44		Inhibition > 50%
	1.37; 2.58 and 5.16	Agar diffusion	Formation of inhibition zone not quantified
Clinic urinary tract infection	0.05	Agar diffusion	8.00 ± 0.24 mm		[35]
	-	Broth microdilution	Not detected
ni	Ni; (5 mL colloidal solution)	Agar diffusion	17 mm		[13]
ni	10	Agar diffusion	0.0 mm		[21]
	50		~3.33 mm
	100		5.33 mm
MSSA ATCC 29213	-	Macrodilution broth	50 ± 20 µg/mL (planktonic culture)	180 ± 80 µg/mL (biofilm)	[34]
MRSA ATCC 43300	-		70 ± 0.0 µg/mL (planktonic culture)	180 ± 80 µg/mL (biofilm)
NCIM-5022	10 (500 µg/50 µL)	Agar diffusion	1.67 ± 0.33 mm		[22]
	10 (1000 µg/100 µL)		3.33 ± 0.67 mm
NCIM-5022	10	Agar diffusion	0.0 mm		[30]
	0.2 and 0.4	Diluted in broth	No inhibition
NCIM-5022	10 (500 μg/50 μL)	Agar diffusion	0.53 ± 0.12 mm		[17]
	10 (1000 μg/100 μL)		1.47 ± 0.03 mm
Clinical strain	ni (25 µL of solution)	Agar diffusion	5 mm		[14]

CSGR: clinical strain gentamycin-resistant; /disc; Ni: not identified in the paper; MRSA: methicillin-resistant Staphylococcus aureus; MSSA: methicillin-sensitive Staphylococcus aureus; CFU: colony forming unit; in chronological order. Source: original source.