Review Article

Current Knowledge and Recent Advances of Right Ventricular Molecular Biology and Metabolism from Congenital Heart Disease to Chronic Pulmonary Hypertension

Figure 1

Main histological patterns of right ventricular remodeling in the setting of chronic pressure overload. Inflammation involving mononuclear cells and cardiomyocytes hypertrophy are observed at the early stage. Reduced capillary density and myocardial fibrosis are associated with right ventricular maladaptive phenotype.