Catestatin Induces Glucose Uptake and GLUT4 Trafficking in Adult Rat Cardiomyocytes

Figure 2

Cts induces Glut4 translocation to the plasma membrane. (a) Typical confocal images of Glut4 staining. Pseudocolor images better show the fluorescence intensity variation. (b) Bar graph summarizing the immunofluorescence experiments analysis. The peripheral vs internal Glut4 staining was 0.86±0.04 in control (n=21), 1.045±0.045 for Ins (n=18), 1.23±0.08 for Cts (n=16), and 0.84±0.02 for Cts+Wm (n=29). <0.05, <0.001.

(a)

(b)