Current Advances on the Important Roles of Enhancer RNAs in Gene Regulation and Cancer

Figure 1

Schematic representation of eRNA activation and function. Transcriptional activation of enhancer domains is typically triggered by binding to transcription factor (TF). Enhancer RNAs could functionally contribute to gene activation by modulating the stability of enhancer : promoter (E : P) looping via interacting with looping factors.

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