The Role of Periostin in Capsule Formation on Silicone Implants

Figure 4

Levels of CTGF, TGF-β, MPO, and VEGF in silicone implant-induced capsular tissues determined by western blotting (a). A low signal was obtained for CTGF (b) and TGF-β (c) protein in PN-KO mice (), whereas a strong signal was detected in the C57BL/6 mice (). Compared with the control group (), the levels of MPO (d) and VEGF (e) protein were downregulated in the PN-KO group (). Relative expression levels normalized to the housekeeping gene β-actin. .

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