Research Article
Chemoradiotherapy as Definitive Treatment for Elderly Patients with Head and Neck Cancer
Table 1
Patient characteristics;
exact test (2-sided);
earson’s chi-squared test.
| | Patient characteristics | | Characteristics | value |
| | Total number | 158 | | | Median age | 61 (range 36–91) | |
| | | n (%) | |
| | Age ≥ 65 | 58 (37) | | | Age ≥ 70 | 33 (21) | | | Age ≥ 75 | 16 (10) | | | Male | 122 (77) | |
| | | Age < 65 (%) | Age ≥ 65, (%) | |
| | Number | 100 (63) | 58 (37) | | | Tumor localization | | Oral cavity | 31 (31) | 18 (32) | | | Oropharynx | 42 (42) | 20 (34) | | Hypopharynx, larynx | 27 (27) | 20 (34) |
| | p16 positivity | 19/82 (16) | 14/53 (24) | | | (available for , 85%) | | History of smoking | 50/75 (67) | 30/41 (73) | | | (available for , 73%) | | Male | 84 (84) | 38 (66) | | | T2 | 5 (5) | 4 (7) | | | T3 | 24 (24) | 16 (28) | | T4 | 71 (71) | 38 (66) | | N0 | 6 (6) | 10 (17) | | | N1 | 3 (3) | 0 (0) | | N2 | 78 (78) | 45 (78) | | N3 | 4 (4) | 1 (2) | | G1 | 7 (7) | 2 (3) | | | G2 | 77 (77) | 38 (66) | | G3 | 16 (16) | 18 (31) |
| | RT dose (Gy) | 70.6 (59–72.6) | 70.6 (50–74.6) | | | Median (range) | | Concomitant chemotherapy (, 100%) | | Platin-based chemotherapy | 72 (72) | 43 (74) | | | Chemotherapy completion | | 100% | 64 (64) | 32 (55) | | | ≥50% | 31 (31) | 20 (35) | | <50% | 5 (5) | 6 (10) | | ECOG performance status | | 0 | 34 (34) | 13 (22) | | | 1 | 48 (48) | 27 (47) | | 2 | 12 (12) | 8 (14) | | 3 | 1 (1) | 2 (3) | | Not reported | 6 (6) | 8 (14) |
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