Yes-Associated Protein 1 as a Novel Prognostic Biomarker for Gastrointestinal Cancer: A Meta-Analysis

Table 3

Pooled HR for DFS of patients with high expression of YAP1 according to subgroup analyses.

Outcome subgroup	No. of patients	No. of studies	Fixed-effects model		Heterogeneity
			HR (95% CI)	P value	I^2 (%)	P
DFS	869	5	1.33(0.95,1.88)	<0.001	59.9	0.041
Tumor type
ESCC	142	1	1.83(1.12,3.00)	0.016	-	-
GC	582	3	1.18(0.66,2.11)	0.584	76.4	0.014
CRC	145	1	1.17(0.69,1.88)	0.556	-	-
Contry
China	145	1	1.35(0.89,2.06)	0.556	-	-
Korea	724	4	1.17(0.95,1.88)	0.159	67.4	0.027

DFS: disease-free survival; ESCC: esophageal squamous cell carcinoma; GC: gastric cancer; CRC: colorectal cancer; HR: hazard ratio; CI: confidence interval.