Research Article

Serum Adipocyte Fatty Acid-Binding Protein 4 Levels Are Independently Associated with Radioisotope Glomerular Filtration Rate in Type 2 Diabetic Patients with Early Diabetic Nephropathy

Table 3

Correlation analysis for Lg FABP in T2DM patients.

Lg FABP4
r§P§

Sex0.286<0.0001
Age (years)0.1950.015
Diabetes duration (years)0.0950.249
BMI (kg/m2)0.2720.001
WC (cm)0.292<0.0001
SBP (mmHg)0.1900.023
HbA1c (%)0.0680.4270.2050.022
TC (mmol/L)0.0040.961−0.1380.133
TG (mmol/L)0.1400.0860.0810.355
HDL (mmol/L)0.0920.2600.1320.129
LDL (mmol/L)−0.0280.7340.0190.830
RBP4 (mg/L)0.0820.3370.0010.987
rGFR (mL/min/1.73 m2)−0.350<0.0001−0.349<0.0001
hsCRP (mg/L)0.1480.0830.1660.162
UACR (μg/mg)0.0570.4810.0670.435
Cys-C/Cr (μg/mg)0.0090.9150.0420.633
NGAL/Cr (μg/mg)0.1340.0970.0820.340

-transformed variables; Pearson correlation analysis for normally distributed variables; Spearman correlation analysis for non-normally distributed variables; §adjustment for sex, age, BMI, WC, and SBP used partial correlation analysis. FABP4, fatty acid-binding protein 4; BMI, body mass index; WC, waist circumference; SBP: systolic blood pressure; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein; RBP4, retinal-binding protein 4; rGFR, radioisotope glomerular filtration rate; hsCRP, high-sensitivity C-reactive protein; UACR, urinary albumin-to-creatinine ratio; Cys-C/Cr, cystatin C-to-creatinine ratio; NGAL/Cr, neutrophil gelatinase associated lipocalin-to-creatinine ratio.