Research Article
SIRT7 Regulates the Vascular Smooth Muscle Cells Proliferation and Migration via Wnt/β-Catenin Signaling Pathway
Figure 3
The effects of SIRT7 knockdown, overexpression, or treatment with DKK-1 on HAVSMCs proliferation stimulated by ox-LDL. (a) CCK-8 cell proliferation assay. P < 0.001 versus siRNA-NC; P < 0.05 and P < 0.001 versus Vector-NC; P < 0.05 versus Vector-SIRT7. (b) Cell cycle distribution (%) in G1, S, and G2 phases. P < 0.05 and P < 0.001 versus siRNA-NC; P < 0.01 and P < 0.001 versus Vector-NC; P < 0.05 versus Vector-SIRT7. (c) Cell cycle analysis.
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