Combination of Genetic Markers and Age Effectively Facilitates the Identification of People with High Risk of Preeclampsia in the Han Chinese Population

Table 1

SNPs included in the study and their allele contribution to PE.

Gene	SNP	Reported PE minor allele	Minor PE allele in the study^1
ACE	rs4646994	Del	Not sig.
AGT	rs699	C	Not sig.
	rs4762	T	T
APOE	rs429358	C	Not sig.
	rs7412	T	T
ATIR	rs5186	C	Not sig.
CTLA4	rs231775	G	Not sig.
EPHX1	rs1051740	C	Not sig.
ERAP2	rs2549782	G	G
F2	rs1799963	A	—
FV	rs602	A	Not sig.
	rs6025	A	Not sig.
GSTP1	rs1695	G	Not sig.
IGF1	rs5742620	A	—
IL-10	rs1800896	G	G
LPL	rs1800590	G	—
	rs268	G	—
MTHFR	rs1801133	T	Not sig.
NOS3	27bp-VNTR in intron 4	4a	Not sig.
	rs2070744	C	C
	rs1799983	T	Not sig.
SERPINE1	rs1799889	G	—
TLR4	rs4986790	G	—
	rs4986791	T	—
TNF-alpha	rs1800629	A	A
	rs1799724	T	T
VEGF	rs3025039	T	Not sig.

The minor allele at the locus without polymorphism is represented with ‘—’; not significant allele or genotype composition difference between patients with PE and controls is indicated with “not sig.” (chi-square test, P ≥ 0.1). For significant (P < 0.05) or marginally significant (P ≥ 0.05 and < 0.1) ones, the PE-contributing minor alleles are shown.