Spectral CT Analysis of Solitary Pulmonary Nodules for Differentiating Malignancy from Benignancy: The Value of Iodine Concentration Spatial Distribution Difference

Table 3

Diagnostic indices of NICpro, dNIC in PP, AP, and VP, and other methods for differentiating malignant and benign SPNs.

Criteria	AUC	Sensitivity	Specificity	TP	FP	FN	TN	PPV	NPV (%)
		(%)	(%)					(%)
NICpro(PP)>0.40	0.644	77	57	26	13	13	8	67	38
NICpro(AP)>0.47	0.716	67	57	3	0	36	21	100	37
NICpro(VP)>0.36	0.714	89	52	35	10	4	11	78	73
dNIC(PP) >-0.35	0.923	92	95	37	13	1	9	74	90
dNIC(AP) >0.00	0.924	89	90	35	2	4	19	94	82
dNIC(VP) >-0.07	0.933	93	95	37	1	2	20	97	90
Visual assessment (conventional CT)	0.707	79	62	31	8	8	13	79	62