Synergistic Effect of Endogenous and Exogenous Aldehydes on Doxorubicin Toxicity in Yeast

Table 1

Statistical analysis of wild type survival in response to formaldehyde and doxorubicin treatment.

Treatment		% Survival ± SEM	Expected value, %	Fold Sensitivity	value
Form (mM)	Doxo (μM)
0	0	100	-	1	1
2	0	78 ± 13.9	-	1.2	0.2513
0	10	62 ± 13.6	-	1.6	0.038
0	50	58 ± 16.2	-	1.7	0.049
0	150	11 ± 3.2	-	9	<0.0001
2	10	2 ± 1.1	48	50	0.0001
2	50	5 ± 4.2	45	20	0.0019
2	150		8.5	1000	<0.0001