Synergistic Effect of Endogenous and Exogenous Aldehydes on Doxorubicin Toxicity in Yeast

Table 3

Statistical analyses of formaldehyde and doxorubicin relative to the actual percent survival. value less than 0.05 is statistically significant.

	% Survival ± SEM	Relative to Form (2 mM) Alone		Relative to Doxo (10 μM) Alone
		Fold sensitivity	value	Fold sensitivity	value
msh2		5.2	0.0090	3.6	0.0016
siz1	23.2 ± 2.8	3.5	0.0001	2.3	0.0004
Wild type	1.89 ± 1.1	41.0	0.0002	32.7	0.0004