Hypoxia Enhances Fusion of Oral Squamous Carcinoma Cells and Epithelial Cells Partly via the Epithelial–Mesenchymal Transition of Epithelial Cells

Figure 4

(a) The expression of EMT-associated indexes including N-cadherin, E-cadherin, Vimentin, and Slug with/without hypoxia or DAPT stimulation. (b) The number of fused cells by artificial cell counting with/without the pretreated of hypoxia or DAPT for 3 days. (c) The fusion rate of the pretreated group and the control group by FACS. (i) Hypoxia (−), DAPT (−); (ii) hypoxia (−), DAPT (+); (iii) hypoxia (+), DAPT (−); (iv) hypoxia (+), DAPT (+). (d) Statistical analysis of fusion rate of the pretreated group and the control group ().

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