Association between Polymorphisms of Antioxidant Gene (MnSOD, CAT, and GPx1) and Risk of Coronary Artery Disease

Table 5

Association between MnSOD genotypes and risk of coronary artery disease severity stratified by cigarette smoking status.

	CAD severity
	0	1	2	3
Never cigarette smoking
MnSOD
Val/Val	109	51	48	51
Val/Ala+Ala/Ala	20	20	14	10
OR(95% CI)^a	1.00	2.07(0.98-4.37)	1.91(0.81-4.52)	1.45(0.58-3.62)
P-value		0.056	0.140	0.431
Ever cigarette smoking
MnSOD
Val/Val	72	67	54	80
Val/Ala+Ala/Ala	9	20	13	18
OR(95% CI)^a	1.00	2.63(1.07-6.44)	2.11(0.81-5.54)	1.73(0.69-4.36)
P-value		0.034	0.129	0.245

a: adjusted for age, sex, and alcohol drinking.