Inflammatory Cellular Response to Mechanical Ventilation in Elastase-Induced Experimental Emphysema: Role of Preexisting Alveolar Macrophages Infiltration

Figure 1

Design of experimental groups. C57BL/6 mice received a tracheal instillation of either elastase (Elastase mice) or saline (Saline mice). After 14 or 21 days, mice were anesthetized, intubated, subjected to either spontaneous ventilation (SV mice) or mechanical ventilation (MV mice), and then sacrificed after two hours.