Differential Modulation of Transcription Factors and Cytoskeletal Proteins in Prostate Carcinoma Cells by a Bacterial Lactone

Figure 4

C12-HSL inhibits cell migration. Wound healing assays with PC3, DU145, and RWPE1 cells in the presence of C12-HSL (50 μmol/L) for 48 h. In untreated cells, the wound closure was complete. In the presence of C12-HSL no wound gap closure was observed. ns, not significant; . Red arrows depict the movement of RWPE1 cells into the wound space.