Optical Coherence Tomography Angiography versus Dye Angiography in Age-Related Macular Degeneration: Sensitivity and Specificity Analysis

Figure 2

Multimodal imaging of a false negative case. (a) Late-frame fluorescein angiography displaying a small area of dye leakage superiorly to a central area of hypofluorescence. (b) Late-frame indocyanine green angiography confirms the presence of a neovascular plaque superiorly to the central area of deep hypocyanescence. (c-d) B-scan optical coherence tomography demonstrates a high serous pigment epithelium detachment (PED) with evidence of a poorly reflective tissue under the retinal pigment epithelium (white arrow) and subretinal fluid. A small rip of the retinal pigment epithelium could be suspected (e) OCT angiography scans: evidence of flow signal neither at the outer retina layer nor at the choriocapillaris layer due to the masking artifact of the PED.

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