Association of Angiogenic and Inflammatory Markers with Power Doppler Ultrasound Vascularity Grade and DAS28-CRP in Early Rheumatoid Arthritis: A Comparative Analysis
Table 3
(a) Logistic regression analysis of PDUS with selected clinical features
Dependent Variables
PDUS
R2
0.5320
Significance Level
0.0001
Variable
Coefficient
Std.Error
Wald
P
Odds ratio
95CI
ANG-1
-0.0066069
0.0038852
2.8919
0.0890
0.9934
0.9859 to 1.0010
ANG-2
-0.000063268
0.000086613
0.5336
0.4651
0.9999
0.9998 to 1.0001
TNF-α
0.0012117
0.00055438
4.7775
0.0288
1.0012
1.0001 to 1.0023
VEGF
0.0079439
0.0035127
5.1142
0.0237
1.0080
1.0011 to 1.0149
(b) Multiple linear regression analysis of DAS28 CRP with selected clinical features
Dependent Variables
DAS28 CRP
Coefficient of determination R2
0.1
R2-adjusted
0.02
Multiple correlation coefficient
0.32
Model 1
Independent variables
b
Std Error
rpartial
t
p value
ANG-2
0.0003466
0.0009471
0.05572
0.366
0.7162
ANG-1
0.00002395
0.00002459
0.1469
0.974
0.3355
TNF-α
0.0001029
0.00008316
0.1854
1.237
0.2228
VEGF
-0.0005151
0.0003407
-0.2247
-1.512
0.1378
R2, multiple coefficient of determination; b standard regression coefficient. For abbreviations refer to Table 2.