MicroRNA Expression Profiling in Psoriatic Arthritis

Figure 3

Comparison of deregulated miRNAs target genes with PsA-associated transcriptional profiles. (a) Pie chart showing percentages of DEGs in PsA from [8] not targeted or targeted by PsA only active and PsA common deregulated miRNAs. DEGs targeted by two or more miRNAs with different modulation in PsA (up- and downmodulated) are defined as “targeting: both opposite and concordant.” (b) Protein-protein interaction (PPI) network of DEGs in PsA patients (from [8]). (c) Modules originated from the interaction network. Genes targeted by deregulated miRNAs are highlighted in red.

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