Review Article
Prognostic Significance of Platelet-to-Lymphocyte Ratio in Cholangiocarcinoma: A Meta-Analysis
Table 4
Meta-analysis of the association between PLR and clinicopathological features of CCA.
| Characteristics | No. of studies | No. of patients | OR (95% CI) | p | Heterogeneity | I2 (%) | Ph |
| Age (≥ median vs. < median) | 3 | 669 | 0.82 (0.38-1.77) | 0.61 | 70 | 0.03 | Gender (male vs. female) | 4 | 789 | 0.59 (0.44-0.80) | < 0.001 | 0 | 0.94 | CA199 (>37 ng/mL vs. <37 ng/mL) | 3 | 669 | 1.25 (0.92-1.70) | 0.16 | 0 | 0.56 | Differentiation (low vs. moderate/high) | 2 | 442 | 1.05 (0.64-1.73) | 0.85 | 0 | 0.90 | Lymph node metastasis (pos vs. neg) | 4 | 1194 | 1.16 (0.82-1.65) | 0.39 | 0 | 0.63 | Vascular invasion (pos vs. neg) | 2 | 978 | 1.27 (0.86-1.89) | 0.23 | 0 | 0.56 | Postoperative complication (present vs. absent) | 2 | 776 | 1.44 (0.97-2.14) | 0.07 | 0 | 0.39 | Postoperative mortality (present vs. absent) | 2 | 776 | 1.54 (0.56-4.26) | 0.41 | 0 | 0.67 | Margin status (R1 vs. R0) | 2 | 776 | 2.09 (1.24-3.54) | 0.006 | 0 | 0.69 |
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R0: microscopically negative resection margins; R1: microscopically positive resection margins.
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