Review Article

Prognostic Significance of Platelet-to-Lymphocyte Ratio in Cholangiocarcinoma: A Meta-Analysis

Table 4

Meta-analysis of the association between PLR and clinicopathological features of CCA.

Characteristics No. of studiesNo. of patientsOR (95% CI)pHeterogeneity
I2 (%)Ph

Age (≥ median vs. < median)36690.82 (0.38-1.77)0.61700.03
Gender (male vs. female)47890.59 (0.44-0.80)< 0.00100.94
CA199 (>37 ng/mL vs. <37 ng/mL)36691.25 (0.92-1.70)0.1600.56
Differentiation (low vs. moderate/high)24421.05 (0.64-1.73)0.8500.90
Lymph node metastasis (pos vs. neg)411941.16 (0.82-1.65)0.3900.63
Vascular invasion (pos vs. neg)29781.27 (0.86-1.89)0.2300.56
Postoperative complication (present vs. absent)27761.44 (0.97-2.14)0.0700.39
Postoperative mortality (present vs. absent)27761.54 (0.56-4.26)0.4100.67
Margin status (R1 vs. R0)27762.09 (1.24-3.54)0.00600.69

R0: microscopically negative resection margins; R1: microscopically positive resection margins.