miR-548b-3p Regulates Proliferation, Apoptosis, and Mitochondrial Function by Targeting CIP2A in Hepatocellular Carcinoma

Figure 3

miR-548b-3p regulates cisplatin sensitivity and mitochondrial membrane potential. (a) In Huh7 cells treated with cisplatin, miR-548b-3p mimic increased the rate of apoptosis. In contrast, miR-548b-3p inhibitor downregulated CDDP-induced apoptosis rate in SK-Hep-1 cells. (b) JC-1 staining showed that miR-548b-3p mimic upregulated the percentage of green fluorescence, which indicated MMP decrease. In contrast, miR-548b-3p inhibitor downregulated the percentage of green fluorescence.

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