miR-548b-3p Regulates Proliferation, Apoptosis, and Mitochondrial Function by Targeting CIP2A in Hepatocellular Carcinoma

Figure 5

miR-548b-3p regulates proliferation via CIP2A. (a) Western blot demonstrated that CIP2A siRNA depletion downregulated c-myc expression in SK-Hep-1 cells treated with miR-548b-3p inhibitor. The effect of CIP2A siRNA on c-myc was not significant in Huh7 cells treated with miR-548b-3p mimic. (b) MTT assay showed that CIP2A depletion could abolish the effect of miR-548b-3p inhibitor on proliferation in SK-Hep-1 cells. The effect of CIP2A siRNA was not significant in Huh7 cells treated with miR-548b-3p mimic.

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