Managing Severe Asthma: A Role for the Long-Acting Muscarinic Antagonist Tiotropium

Figure 1

Stepwise asthma management in adults, adolescents, and children aged 6–11 years. Notes. Not for children aged 12 years; for children aged 6–11 years (preferred Step 3 treatment medium-dose ICS); for patients prescribed BDP/formoterol or BUD/formoterol maintenance and reliever therapy; tiotropium by mist inhaler is an add-on treatment for patients aged ≥12 years with a history of exacerbations. Copyright ©2018 Global Initiative for Asthma. Reproduced with permission from. Global Initiative for Asthma. Global strategy for asthma management and prevention. 2018. Abbreviations. BDP, beclomethasone dipropionate; BUD, budesonide; ICS, inhaled corticosteroid; LABA, long-acting β₂-agonist.