Development of a Rat Model of Sick Sinus Syndrome Using Pinpoint Press Permeation

Figure 3

Changes in heart rates at different time points. Compared to the control group, heart rates in the SSSA group were gradually restored to preoperative values within 4 weeks. For the SSSB group, heart rates first decreased by 31–40% and stabilized after 2-3 weeks but were lower than the preoperative values. Heart rates of surviving rats in the SSSC group were restored by 35% of the preoperative values within 4 weeks.