The CD40 rs1883832 Polymorphism Affects Sepsis Susceptibility and sCD40L Levels

Table 1

General characteristics of the sepsis patients and healthy controls.

Parameter	Sepsis ()	Controls ()
Gender (male/female)	175/86	208/114	NS
Age, year	56.45 ± 10.23	57.36 ± 11.66	NS
BMI, kg/m^2	23.51 ± 2.72	23.85 ± 1.95	NS
SBP, mmHg	128 ± 14	122 ± 18	NS
DBP, mmHg	80 ± 6	84 ± 10	NS
History of smoking	95	106	NS
History of drinking	102	124	NS
APACHE II score	22.3 ± 4.2	N.A
SOFA score	8.1 ± 1.5	N.A
Sepsis status
Sepsis, (%)	57 (21.8)	N.A
Septic shock, (%)	64 (24.5)	N.A
Severe sepsis, (%)	140 (53.7)	N.A
Pathogens, (%)
Gram-positive	45 (17.2)	N.A
Gram-negative	85 (32.6)	N.A
Mixed Gram-positive and Gram-negative	79 (30.3)	N.A
Fungus	36 (13.8)	N.A
Negative blood cultures	16 (6.1)	N.A
Source of infection
Lung	141 (54.0)	N.A
Blood	24 (9.2)	N.A
Abdomen	55 (21.1)	N.A
Urinary tract	14 (5.4)	N.A
Catheter-related	7 (2.7)	N.A
Trauma	14 (5.4)	N.A
Others	6 (2.3)	N.A
28-day mortality, (%)	93 (35.6)	N.A