Microcrystalline Cellulose for Delivery of Recombinant Protein-Based Antigen against Erysipelas in Mice

Figure 6

Cumulative mortality of immunized mice after challenge. Mice were vaccinated with free CBD-SpaA, Avicel coated with CBD-SpaA, and ERT2T-A containing whole cell bacterin as a positive control and PBS as a negative control. After 14 days, all the mice were challenged with highly virulent E. rhusiopathiae and survival was monitored for ten days.