Review Article
Comparative Analysis of ADR on China’s National Essential Medicines List (2015 Edition) and WHO Model List of Essential Medicines (19th Edition)
Table 1
The occurrence of ADR with medicines recorded in China’s and WHO list.
| Drug classification | WHO model list | China’s list | The same number | WHO essential medicines | China essential medicines | ADR cases | Composition% | ADR cases | Composition% |
| Anti-infective | 76 | 55 | 27 | 18128 | 37.52 | 24735 | 32.43 | Anthelminthics | 31 | 9 | 7 | 495 | 1.02 | 937 | 0.23 | anaesthetics | 13 | 4 | 2 | 455 | 0.94 | 28 | 0.03 | Medicines for pain and palliative care | 34 | 18 | 4 | 4089 | 7.65 | 6469 | 8.48 | The nervous system | 9 | 18 | 7 | 959 | 1.99 | 3116 | 4.08 | Medicines used in mood disorders | 14 | 6 | 3 | 2768 | 5.73 | 516 | 0.68 | Cardiovascular | 21 | 31 | 13 | 1958 | 4.05 | 6146 | 8.06 | Respiratory medicines | 5 | 8 | 1 | 229 | 0.47 | 3103 | 4.07 | Gastrointestinal medicines | 10 | 29 | 4 | 1673 | 3.46 | 4308 | 5.65 | Urinary medicines | 5 | 7 | 3 | 971 | 2.01 | 592 | 0.78 | Medicines affecting the blood | 22 | 16 | 4 | 657 | 1.36 | 1698 | 2.23 | Endocrine medicines | 23 | 21 | 4 | 1398 | 3.10 | 1941 | 2.54 | Antiallergic medicines | 5 | 5 | 1 | 983 | 2.04 | 1111 | 1.46 | Immune system medicines | 4 | 2 | 1 | 61 | 0.13 | 82 | 0.11 | Vitamins, minerals | 12 | 15 | 2 | 110 | 0.23 | 2156 | 2.83 | Adjust water, electrolyte and acid base balance | 9 | 9 | 6 | 11266 | 23.87 | 15762 | 20.66 | Antidotes | 15 | 6 | 3 | 203 | 0.48 | 132 | 0.17 | Biological products | 8 | 4 | 2 | 28 | 0.06 | 1098 | 1.44 | Diagnostic agents | 7 | 2 | 1 | 326 | 0.68 | 32 | 0.04 | Dermatological medicines | 16 | 12 | 9 | 730 | 1.51 | 418 | 0.55 | Ophthalmic medicines | 13 | 13 | 9 | 142 | 0.29 | 439 | 0.57 | Ear and nose medicines | 4 | 3 | 0 | 68 | 0.14 | 70 | 0.09 | obstetrics and gynecology medicine | 4 | 7 | 3 | 515 | 1.07 | 1260 | 1.65 | Family planning medicines | 13 | 1 | 1 | 98 | 0.20 | 133 | 0.17 | | 373 | 301 | 117 | 48310 | 100 | 76282 | 100 |
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Note: repeat medication for one
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